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Fluoxetine is possible to pass into breast milk and so can do harm to a nursing baby. Limited evidence is available concerning the longer-term effects of fluoxetine on the development and maturation of children and adolescent patients. Results of a number of published epidemiological studies assessing the risk of fluoxetine exposure during the first trimester of pregnancy have demonstrated inconsistent results. In addition, fluoxetine treatment was associated with a decrease in alkaline phosphatase levels. In particular, there are no studies that directly evaluate the longer-term effects of fluoxetine on the growth, development and maturation of children and adolescent patients. A lower or less frequent dose of fluoxetine should be used in patients with cirrhosis.
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Thus, fluoxetine may be administered with or without food. The only identified active metabolite, norfluoxetine, is formed by demethylation of fluoxetine. R-norfluoxetine is significantly less potent than the parent drug in the inhibition of serotonin uptake. Plasma concentrations of fluoxetine were higher than those predicted by single-dose studies, because fluoxetine’s metabolism is not proportional to dose. This suggests that the use of fluoxetine in patients with liver disease must be approached with caution. This effect is reversible after cessation of fluoxetine treatment.
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Authority prescriptions need to be applied for by the doctor writing the script and can include reasons such as increased quantities due to dosage, increased repeats, use for a pre determined specified use or the nature of the medication itself requiring specialist interaction. The information contained herein is not intended to cover all possible uses directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. This makes fluoxetine highly effective in treatment of clinical depression cases where symptoms like depressed mood and lack of energy exist. Fluoxetine affects neurotransmitters, the chemicals that nerves within the brain use to communicate with each other. Fluoxetine works by preventing the reuptake of one neurotransmitter, serotonin, by nerve cells after it has been released. Some patients may experience withdrawal reactions upon stopping fluoxetine. The dose of fluoxetine should be gradually reduced when therapy is discontinued.
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Not all possible interactions are listed here. Years of development and testing finally led to approval of fluoxetine for marketing. Three randomized, double-blind, placebo-controlled studies showed a decrease in the frequency and severity of migraine headaches with fluoxetine therapy. Because uptake inactivates serotonin by removing it from the synaptic cleft, uptake inhibition by fluoxetine enhances serotonergic function. Fluoxetine does not interact directly with postsynaptic serotonin receptors, muscarinic-cholinergic receptors, histaminergic receptors, or alpha-adrenergic receptors.
The liver then metabolizes fluoxetine into norfluoxetine, a desmethyl metabolite, which is also a serotonin reuptake inhibitor. Fluoxetine versus other types of pharmacotherapy for depression. Possible involvement of cholinergic and opioid receptor mechanisms in fluoxetine mediated antinociception response in streptozotocin-induced diabetic mice. Plasma catecholamine levels after fluoxetine treatment in depressive patients.
Fluoxetine for migraine prophylaxis: a double-blind trial. Fluoxetine prophylaxis of migraine. A randomized, double-blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia. The fetal safety of fluoxetine: a systematic review and meta-analysis.
Fluoxetine attenuates alcohol intake and desire to drink. Fluoxetine monotherapy in attention-deficit/hyperactivity disorder and comorbid non-bipolar mood disorders in children and adolescents. Double-blind trial of fluoxetine: chronic daily headache and migraine. Fluoxetine and premature ejaculation: a double-blind, crossover, placebo-controlled study. Double-blind placebo-controlled trial of fluoxetine in smoking cessation treatment including nicotine patch and cognitive-behavioral group therapy. The effect of fluoxetine in patients with pain and constipation-predominant irritable bowel syndrome: a double-blind randomized-controlled study. Fluoxetine and fluvoxamine for treatment of chronic pain.
Fluoxetine for the treatment of childhood anxiety disorders. The effects of fluoxetine in the overdose patient. Benign course in a child with a massive fluoxetine overdose. Timing of onset of antidepressant response with fluoxetine treatment. Use of fluoxetine in anorexia nervosa before and after weight restoration. These studies indicate that fluoxetine may help to treat depression and obsessive-compulsive disorder in children. Fluoxetine works by affecting a part of your brain that controls your mood.
However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. Fluoxetine is used to treat depression, obsessive-compulsive disorders, panic disorder, and bulimia (binge eating and purging). Fluoxetine affects chemicals in the brain that may become unbalanced and cause depression or mood disturbances, eating disorders, or obsessive or compulsive symptoms. While you are taking fluoxetine you may need to be monitored for worsening symptoms of depression and suicidal thoughts at the start of therapy or when doses are changed. Many people still suffer from infections and diseases that could have been easily cured by existing medication, such as natural cream for skin problems, or tables for oral intake that prevent urinary tract infections.
Fluoxetine dosage will change for different people. Mature people, or anyone that requires numerous prescription drugs daily, have reached exposure to possible medication interactions which usually trigger the signs of major depression. For many individuals the best solution for the treatment of depressuin is to buy fluoxetine online which unfortunately is one of the most effective medications in the market. Fluoxetine should be offered to a child or young person with moderate to severe major depressive disorder only in combination with psychological therapy. Additionally, only limited information concerning the long-term safety of fluoxetine on growth, puberty, mental, emotional and behavioural development in this age group is available. This medicine may affect the way some other medicines work (interaction).
In addition, do not start fluoxetine in a patient who is being treated with linezolid or intravenous methylene blue due to risk of serotonin syndrome. Treatment with fluoxetine and any concomitant serotonergic agents should be discontinued immediately if the above reactions occur, and supportive symptomatic treatment should be initiated. Fluoxetine should be introduced with care in patients with a history of seizures. Rarely have patients discontinued treatment with fluoxetine because of anorexia or weight loss. Patients should be monitored for these symptoms when discontinuing treatment with fluoxetine. Fluoxetine delayed-released capsules are usually taken once a week. Take fluoxetine at around the same time(s) every day.
Continue to take fluoxetine even if you feel well. If you suddenly stop taking fluoxetine, you may experience withdrawal symptoms such as mood changes, irritability, agitation, dizziness, numbness or tingling in the hands or feet, anxiety, confusion, headache, tiredness, and difficulty falling asleep or staying asleep. Your doctor will probably tell you that you should not take fluoxetine. If you become pregnant while taking fluoxetine, call your doctor. Samen met uw arts kunt u besluiten dat het voor u beter is om het gebruik van fluoxetine geleidelijk stop te zetten zolang u zwanger bent. The information is not intended to cover all possible uses directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else.
Geef aan de apotheker door dat u overgevoelig bent voor fluoxetine. Ook als u gewend bent geraakt aan fluoxetine, kunt u door het gebruik van alcohol erg suf worden. Fluoxetine kan de werking van de bloedverdunner versterken. Als u een van deze medicijnen samen met fluoxetine gebruikt, heeft u de eerste weken een verhoogde kans op een tekort aan natrium in het bloed. Fluoxetine kan de hoeveelheid metoprolol in het bloed verhogen.
Fluoxetine versterkt de werking en bijwerkingen van deze medicijnen. Fluoxetine kan de hoeveelheid clozapine in het bloed verhogen en hierdoor de bijwerkingen van clozapine versterken. Fluoxetine kan het effect van tamoxifen verminderen. Fluoxetine kan de bijwerkingen van perfenazine versterken, zoals sufheid en bewegingsstoornissen. Fluoxetine kan de hoeveelheid van deze medicijnen in het bloed verhogen. Fluoxetine kan de werking van atomoxetine versterken.
Bij stoppen met fluoxetine kan de werking van atomoxetine afnemen. Deze mag u niet samen met fluoxetine gebruiken. Andersom duurt het twee weken voor u, na stoppen met deze medicijnen, met fluoxetine mag beginnen. Oorzaak: ik slik minder fluoxetine, en daardoor slaap ik weer. I have noticed that in the prescription of the fluoxetine tablets it says that fluoxetine should be spread out and be taken one in the morning and one in the night.